Vitamin D Decreased Breast Cancer Risk
1. The Annual meeting of the American Association for Cancer Research reported on a meta analysis of 2,274 wonmen with breast cancer and 2,268 women without breast cancer.
2. The meta-analysis included 4 studies.
A. The studies seemed to indicate a inverse dose-response gradient between 25(OH)D (Vit D) levels and the risk of developing breast cancer. The lower the vitamin D level the more likely the patient will develop breast cancer
B. When the studies were combined, a dose-response gradient was observed between serum25(OH)D and risk of breast cancer and was consistent across all studies.
C. The authors suggest that the standard should be raised for Vit D to 30ng/ml or more
D. The authors stated that, "We could prevent half of the breast cancers in the US by raising the serum vitamin D levels to 32ng/mL".
E. There are opposing researchers that state that the analysis was too selective, did not include negative studies, and that it does not prove 'causation' or that the findings do not prove that elevated Vit D will prevent breast cancer